Want to be part of our science?
We collaborate with some of the world’s leading academic, research and clinical teams to advance our understanding of mental health and public health, and how the Orpheus Decoupling Process can be applied to help people. If you are interested in collaborating, please contact us here. Each collaboration is subject to individual agreements and must be approved by Orpheus before commencing. Our standard research use licence can be found here.
Now recruiting
🔬 Edge Hill University Study 2026
A 12-week evaluation, run in partnership with Edge Hill University, assessing whether the Orpheus app produces sustained improvements in symptoms of mild to moderate anxiety and depression. Fifty participants will use the app over 12 weeks alongside five short check-in questionnaires, with ethical oversight provided independently by Edge Hill University.
Take part in this studyThis builds directly on Edge Hill’s earlier published pilot study of Orpheus in student wellbeing services (see our Publications page), extending the evaluation to a longer follow-up period and a broader participant group.
Learn more and applyWe’re continually working with academic and clinical partners to expand the evidence base for the Orpheus Decoupling Process. As new studies launch, they’ll appear here.
Completed Research Projects
Studies we’ve run ourselves that have since finished.
🎓 Edge Hill University Wellbeing Service Pilot
A pilot evaluation of Orpheus run through the Student Wellbeing Service at Edge Hill University. Twenty-six students used the app across 39 completed sessions, with statistically significant reductions in anxiety and depression scores.
🇲🇽 Mexico National Institute of Neurology and Neurosurgery PTSD Pilot
An open-label pilot study testing the Orpheus-style finger-tapping and audio intervention with 10 patients who met the criteria for PTSD, with statistically significant improvements across every measure used after a single session.
Both studies are described in full, alongside our evidence tiering and commentary, on the Publications page.

